Updated October 2026 · 9 picks
Neapolitan blistered crusts, New York slices and square-cut Detroit pies: the Upstate's pizza scene runs deep. These are the spots locals argue about, from downtown Greenville to Spartanburg and Clemson.
Sidewall's thin, blistered Neapolitan-leaning pies made it a Swamp Rabbit Trail favorite, and the Travelers Rest original still has a laid-back main-street feel. It's the obvious stop after a ride or walk on the trail, with sister shops downtown and in Simpsonville.
(1,800 reviews) · 35 S Main St, Travelers Rest, SC 29690 · (864) 610-0527 · sidewallpizza.com
View listingWood-fired, Neapolitan-style pies come out of the ovens at this Village of West Greenville spot, which leans on local ingredients and rotating seasonal specials. Indoor and patio seating make it a relaxed hangout in one of Greenville's most walkable arts districts.
(768 reviews) · 1254 Pendleton St, Greenville, SC 29611 · (864) 412-8501 · coastalcrust.com
View listingThis Charleston-born pizzeria brings creative signature pies, calzones and subs to Greenville, plus a build-your-own option with dozens of toppings. Its Charleston flagship has landed on national best-pizza rankings, and the Greenville shop keeps the same playful menu.
(888 reviews) · 17 Mohawk Dr, Greenville, SC 29609 · (864) 252-4700 · dalspizzagvl.com
View listingOne of Greenville's longest-running pizzerias, Tito's sticks to classic pies while mixing in crowd-pleasers like a hot-honey pepperoni and a vodka-sauce MVP. Big sampler platters and lasagna round out a menu built for family dinners.
(1,462 reviews) · 2018 N Pleasantburg Dr, Greenville, SC 29609 · (864) 523-8747 · titospizzeria.com
View listingBada Bing serves New York-style pies and big foldable slices along the busy Woodruff Road corridor. The loaded house-namesake pizza and buttery garlic knots are the go-to orders.
(641 reviews) · 1860 Woodruff Rd, Ste G, Greenville, SC 29607 · (864) 234-1515 · badabingpizzeriagreenville.com
View listingParcheggio builds its pies on San Marzano tomatoes, fresh mozzarella and pecorino, with fun specialty pizzas like a vodka-sauce pepperoni. It ranks at the top of diner-rated pizza lists for the Greenville area.
(429 reviews) · 2038 Laurens Rd, Ste C, Greenville, SC 29607 · (864) 979-3155 · parcheggio.pizza
View listingSince 1995 this no-frills downtown Spartanburg shop has served big, thin New York-style slices, calzones and cheese bread. Locals regularly call it the best pizza in the Hub City, and by-the-slice lunches keep it affordable.
(1,821 reviews) · 400 E Main St, Spartanburg, SC 29302 · (864) 582-4200 · venuspie.com
View listingClemson's go-to late-night slice shop turns out thin New York-style pizza, garlic knots, stuffed pies and strombolis a block from downtown's bars. Wednesday dollar slices make it a student-and-game-day staple.
(448 reviews) · 105 Sloan St, Clemson, SC 29631 · (864) 654-3001 · todaropizza.com
View listingSumma Joe's anchors downtown Anderson with pizza, pasta and shareable Italian comfort food in generous portions. Specialty pies like the Bob Marley and an All American are best sellers, and the casual room works well for groups and families.
(697 reviews) · 125 N Main St, Anderson, SC 29621 · (864) 712-7595 · summajoes.com
View listingHow we picked: places that show up again and again in local and national coverage (Michelin Guide, Southern Living, Visit Greenville SC and others), cross-checked to make sure they're open in 2026.
Cover photo: Ivan Torres on Unsplash.
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